How to avoid the fouling problems of HFF when used in most perfusion systems?

Very simple - use a LASER guided diaphragm Single-Use-Pump (SUP) able to repeatedly flush out debris, accumulation on the lumen wall.

Here shown some of the scalable SUP span from the small Thalia M80 and up.

Check out on the BPI in Boston September 18-21, 2023.

Check out https://perfusecell.com/products/diaphragm-sups-32

With kind regards from
Per Stobbe